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Intrarticular Sodium Hyaluronate for the Treatment of Osteoarthritis of the Knee.A Restropective Review of 45 Patients.

Yoga, R., and Mukaram, M., and Ramachandran, . (2009) Intrarticular Sodium Hyaluronate for the Treatment of Osteoarthritis of the Knee.A Restropective Review of 45 Patients. Malaysian Orthopaedic Journal, 3 (2). pp. 4-7. ISSN 1985 2533

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Official URL: http://www.morthoj.org/

Affiliations

Orthopaedic Surgery, HSAJB, Johor Bahru, Malaysia
Orthopaedic Surgery, HSAJB, Johor Bahru, Malaysia
Rama Orthopaedic Clinic, Johor bahru, Malaysia

Abstract

Intrarticular Hyaluronic Acid was administered to 45 patients with various grades of osteoarthritis in the knee. Following 3 fortnightly injections, these patients were reviewed at 6 weeks and 3 months with regard to their knee pain. We found the most patients (84.4%) has decreased knee pain following these injections. Patients who had severe grade osteoarthritis based on knee radiographs before the injections were less likely to have pain reduction compared to those with milder grade osteoarthritis. Only 4 (8.9%) patients showed no improvement and were subsequently considered for surgery. Many patients did not require any further treatment (24.4%) and the remaining were given analgesia (64.4%) to aid in their pain. One patient required another course of this injection. there were no complications recorded in this study. We concluded that Intrarticular Hyaluronic acid is an easy and safe method to treat osteoarthritis. The short-term outcome with regard to knee pain is good in patients with milder grades of osteoarthritis.

Item Type:Journal
Keywords:Osteoarthritis, Knee, Sodium Hyaluronate, Pain, Radiograph
Subjects:R Medicine, Dentistry, Pharmacy, Nursing
ID Code:10133

1. Snibbe JC, Gambardella, RA. Treatment options for osteoarthritis. Orthopedics, 2005; 28(2 Suppl): 215-20.

2. Aggarwal A, Sempowski, IP. Hyaluronic acid injections for knee osteoarthritis. Systematic review of the literature. Can Fam Physician, 2004; 50: 249-56.

3. Guidolin DD, Ronchetti IP, Lini E, Guerra D, Frizziero L. Morphological analysis of articular cartilage biopsies from a randomized, clinical study comparing the effects of 500-730 kDa sodium hyaluronate (Hyalgan) and methylprednisolone acetate on primary osteoarthritis of the knee. Osteoarthritis Cartilage, 2001; 9(4): 371-81.

4. Meloni F, Milia F, Cavazzuti M, Doria C, Lisai P, Profili S, et al, Clinical evaluation of sodium hyaluronate in the treatment of patients with sopraspinatus tendinosis under echographic guide: Experimental study of periarticular injections. Eur J Radiol,2008; 68(1): 170-3.

5. Turajane T, Labpiboonpong V, Maungsiri S. Cost analysis of intra-articular sodium hyaluronate treatment in knee osteoarthritis patients who failed conservative treatment. J Med Assoc Thai, 2007; 90(9): 1839-44.

6. Adams ME, Lussier AJ, Peyron JG. A risk-benefit assessment of injections of hyaluronan and its derivatives in the treatment of osteoarthritis of the knee. Drug Saf, 2000; 23(2): 115-30.

7. Uthman I, Raynauld JP, Haraoui B. Intra-articular therapy in osteoarthritis. Postgrad Med J, 2003; 79(934): 449-53.

8. Jubb RW, Piva S, Beinat L, Dacre J, Gishen P. A one-year, randomised, placebo (saline) controlled clinical trial of 500-730 kDa sodium hyaluronate (Hyalgan) on the radiological change in osteoarthritis of the knee. Int J Clin Pract, 2003; 57(6): 467-74.

9. Toh EM, Prasad PS, Teanby D. Correlating the efficacy of knee viscosupplementation with osteoarthritic changes on

roentgenological examination. Knee, 2002; 9(4): 321-30.

10. Roman JA, Chismol J, Morales M, Donderis JL. Intra-articular treatment with hyaluronic acid. Comparative study of Hyalgan and Adant. Clin Rheumatol, 2000; 19(3): 204-6.

11. Kotz R, Kolarz G. Intra-articular hyaluronic acid: Duration of effect and results of repeated treatment cycles. Am J Orthop, 1999;28(11 Suppl): 5-7.

12. Bunyaratavej N, Chan KM, Subramanian N. Treatment of painful osteoarthritis of the knee with hyaluronic acid. Results of a multicenter Asian study. J Med Assoc Thai, 2001; 84 Suppl 2: 576-81.

13. Huskisson EC, Donnelly S. Hyaluronic acid in the treatment of osteoarthritis of the knee. Rheumatology (Oxford), 1999; 38(7):602-7.

14. Frizziero L, Govoni E, Bacchini P. Intra-articular hyaluronic acid in the treatment of osteoarthritis of the knee: Clinical and morphological study. Clin Exp Rheumatol, 1998; 16(4): 441-9.

15. Turajane T, Tanavaree A, Labpiboonpong V, Maungsiri S. Outcomes of intra-articular injection of sodium hyaluronate for the treatment of osteoarthritis of the knee. J Med Assoc Thai, 2007; 90(9): 1845-52.

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