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Styryldehydropyrone and Clerodane-Type Diterpene from Croton Argyratush

Norizan Ahmat A.H., and Ikram M. Said, and Jalifah Latip, and Laily B. Din, and Yana Maolana Syah, and Euis H. Hakim, (2007) Styryldehydropyrone and Clerodane-Type Diterpene from Croton Argyratush. Malaysian Journal of Analytical Sciences, 11 (1). pp. 189-192. ISSN 13942506

Full text not available from this repository.

Official URL: http://pkukmweb.ukm.my/~mjas/v11_n1/29_474C1-1.pdf

Affiliations

Universiti Teknologi MARA, Faculty of Applied Sciences
Universiti Kebangsaan Malaysia, Faculty of Sciences and Technology, Centre for Chemical Science and Food Technology
Universiti Kebangsaan Malaysia, Faculty of Sciences and Technology, Centre for Chemical Science and Food Technology
Universiti Kebangsaan Malaysia, Faculty of Sciences and Technology, Centre for Chemical Science and Food Technology
Institut Teknologi Bandung, Dept. of Chemistry
Institut Teknologi Bandung, Dept. of Chemistry

Abstract

Phytochemical study on the roots of Croton argyratus (Euphorbiaceae) has been carried out. Isolation and purification of the methanolic extract afforded a styryldehydropyrone, (+)-goniothalamin and a clerodane-type diterpene, (-)-junceic acid. The structures of these compounds were determined by spectroscopy methods such as mass spectrometry (MS), 1H and 13C NMR and by comparison with those of previously reported data. This paper report s the isolation and elucidation of theabove compounds.

Kajian fitokimia telah dilakukan ke atas akar Croton argyratus (Euphorbiaceae). Isolasi yang dilakukan ke atas ekstrak metanol spesies ini telah berjaya memencilkan dua sebatian iaitu (+)-goniothalamin (sebatian stirildehidropairon) dan (-)- asid junsik (sebatian diterpena jenis klerodan). Elusidasi struktur sebatian-sebatian ini ditentukan menggunakan kaedah spektroskopi seperti spektrometri jisim (SJ), resonan magnet nukleas (RMN) 1H dan 13C dan juga perbandingan dengan literatur. Kertaskerja ini membincangkan tentang pemencilan dan penentuan struktur bagi sebatian-sebatian di atas.

Item Type:Journal
Additional Information:This work was supported by a grant from Malaysian Government under the IRPA scheme (Grant No. 09-02-02-0086-EA 227). The authors wish to thank UiTM for sponsoring one of the authors for her Ph.D study.
Keywords:Croton argyratus, Euphorbiaceae, goniothalamin, junceic acid
Subjects:Q Science
ID Code:1043

1. Ahmad, F. B., Tukol, W. A., Omar, S. and Mohd. Sharif, A. 1991. 5-Acetyl goniothalamin, a styryl dihydropyrone

from Goniothalamus. Phytochemistry. 30(7):2430-2431.

2. Asakawa Y., Toyota, M. & Ueda, A. 1990. Sacculatane- and clerodane-type diterpenoids from the liverworts Porella perottetiana and Heteroscyphus bescherellei. Phytochemistry. 29(7) : 2165-2167.

3. Burkill, I.H. 1966. A Dictionary of the Economic product of the Malay Peninsular. Kuala Lumpur, 1 : 698-699.

4. Cavalheiro, A.J. & Yoshida, M. 2000. 6-[? - rylalkenyl]-5,6-dihydro-a-pyrones from Cryptocarya moschata

(Lauraceae). Phytochemistry. 53: 811-819.

5. Chan, K.M., Rajab, N.F., Ishak, M.H.A., Ali, A.M., Yusoff, K., Din, L.B. & Inayat-Hussain, S.H. 2006. Goniothalamin induces apoptosis in vascular smooth muscle cells. Chemico-Biological Interactions. 159: 129-140.

6. Corner, E.J.H. 1988. Wayside Trees of Malaya. Jilid 1 & 2. United Press Kuala Lumpur.

7. De Fatima, A., Kohn, L. K., de Cavalho, J. e. & Pilli, R. A. 2006. Cytotoxic activity of (S)-goniothalamin and analogues against human cancer cells. Bioorganic & Medicinal Chemistry. 14(3): 622-631.

8. De Heluani, C.S., Catalan, C.A.N., Hernandez, L.R. & Joseph-Nathan, P. 1998. 13C NMR assignments and conformational evaluation of diterpenes from Croton sarcopelatus Muell. Magnetic Resonance in Chemistry. 36 : 947-950.

9. Habashy, R.R., Naim, A.A., Khalifa, A.E. & Al-Azizi, M. 2005. Anti-inflammatory effects of jojoba liquid wax in experimental models. Pharmacological Research.51(2):95-105.

10. Hasan, C.M., Mia, M.Y., Rashid, M.A. and Connolly, J. D. 1994. 5-acetoxyisogoniothalamin oxide, an epoxystyryl lactone from Goniothalamus sesquipedalis. Phytochemistry. 37 (6):1763-1764.

11. Hisham, A., Toubi, M., Shuaily, W., Ajitha Bai, M.D. & Fujimoto, Y. 2003. Cardiobutanolide, a styryllactone from Goniothalamus cardiopelatus. Phytochemistry. 62(4):597-600.

12. Horgen, F.D., Edrada, R.A., Reyes G., Agcaoili, F., Madulid, D.A., Wongpanich, V., Angerhofer, C.K., Pezzuto, J.

M., Soejarto, D.D. & Farnsworth, N.R. 2001. Biological screening of rain forest plot trees from Palawan Island {Philippines). Phytomedicine. 8(1) : 71-81.

13. Maciel, M.A.M., Pinto, A.C., Arruda, A.C., Pamplona, S., Vanderlinde F. A., Lapa, A. J., Echevarria, A., Grynberg, N.F., Colus, I.M.S., Farias, R.A.F., Luna Costa, A.M. & Rao, V.S.N. 2000. Ethnopharmacology, phytochemistry and pharmacology: a successful combination in the study of Croton cajucara. Journal of Ethnopharmacology. 70: 41-55.

14. Melo, P.S., Duran, N., Lima, C.A.H., Brito, A.R.M.S. & Haun, M. 2003. Comparison of a gastroprotective effect of

a diterpene lactone isolated from Croton cajucara with its synthetic derivatives. Journal of Ethnopharmacology. 87(2-

3) : 169-174.

15. Morales, A., Perez, P., Mendoza, R., Compagnone, R. Suarez, A.I., Arvelo, F., Ramirez, J.L. & Castro, I.G. 2005. Cytotoxic and proapoptotic activity of ent-16ß-17a-dihydroxykaurane on human mammary carcinoma cell line MCF-7. Cancer Letters. 218 (1) : 109-116.

16. Mosaddik, M.A., Haque, M.E. & Rashid, M.A. 2000. Goniothalamin from Bryonopsis laciniosa Linn (Cucurbitaceae). Biochemical Systematics and Ecology. 28(10): 1039-1040.

17. Roengsumran, S., Petsom, A., Sommit, D. & Vilaivan, T. 1999. Labdane diterpenoids from Croton oblongifolius. Phytochemistry. 50: 449-453.

18. Sam, T. W., Sew-Yeu, C., Matsjeh, S., Gan, E.K., Razak, D. & Mohamed, A.L. 1987. Goniothalamin oxide: An embryotoxic compound from Goniothalamus macrophyllus (annonaceae). Tetrahedron Letters. 28(22): 2541-2544.

19. Silva, R.M., Oliveira, F.A., Cunha, K.M.A., Maia, J.L., Maciel, M.A.M., Pinto, A.C., Nascimento, N.R.F., Santos, F.A. & Rao, V.S.N. 2005. Cardiovascular of trans-dehydrocrotonin, a diterpene from Croton cajucara in rats. Bioorganic & Medicinal Chemistry. 13: 4238-4242.

20. Suárez, A.I, Blanco, Z., Compagnone, R.S., Salazar-Bookaman, M.M., Zapata, V & and Alvarado, C. 2006. Antiinflammatory activity of Croton cuneatus aqueoous extract. Journal of Ethnopharmacology. 105 (1-2) : 99-101.

21. Sundby, E., Perk, L., Anthonsen, T., Aasen, A.J. & Hansen, T. V. 2004. Synthesis of (+)-goniothalamin and its enantiomer by combination of lipase catalyzed resolution and alkene metathesis. Tetrahedron. 60: 521-524.

22. Sutthivaiyakit, S., Nareeboon, P., Ruangrangsi, N., Ruchirawat, S., Pisutjaroenpong, S. & Chulaborn, M. 2001. Labdane and primarane diterpenes from Croton cajucara. Phytochemistry. 56: 811-814.

23. Sylvestre, M., Pichette, A., Longtin, A., Nagau, F. & Lagault, J. 2006. Essential oil analysis and anticancer activity of leaf essential oil of Croton flavens L. from Guadeloupe. Journal of Ethnopharmacology. 103(1) : 99-102.

24. Umar Tsafe, N., Mohamed Said, M.S., Rosli, R., Din, l. B. & Lai, L. C. 2004. Genotoxicity of goniothalamin in CHO cell lines. Genetic Toxicology and Environment Mutagenesis. 562: 91-102.

25. Whitmore, T.C. 1972. Tree Flora of Malaya. Longman. 2 : 84-85.

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