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Seroprevalence of Malassezia furfur in an urban population in Malaysia

Chua, Kaw Bing, and Shamala Devi, and Hooi, Poh Sim, and Chong, Kwai Hoe, and Phua, Kai Lit, and Mak, Joon Wah, (2003) Seroprevalence of Malassezia furfur in an urban population in Malaysia. Malaysian Journal of Pathology, 25 (1). pp. 49-56. ISSN 0126-8635

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Official URL: http://www.mjpath.org.my/past_issue/MJP2003.1/Malassezia%2006.pdf

Affiliations

International Medical University, Kuala Lumpur
University Malaya Medical Centre. Dept. of Medical Microbiology
University Malaya Medical Centre. Dept. of Medical Microbiology
International Medical University, Kuala Lumpur
International Medical University, Kuala Lumpur
International Medical University, Kuala Lumpur

Abstract

An in-house prepared M. furfur antigen was used to carry out a seroprevalence study in an urban population in Malaysia by indirect immunofluorescence assay. Of the 800 serum samples from all ages screened, 738 samples were positive for M. furfur specific IgG, giving an overall seropositive rate of 92.3%. There was no significant difference in the seropositive rates among the different gender group and races. However, there was a statistical significant difference in the seropositive rate among different age groups with a lower rate (73%) for the age group 5 years old and below, which increased rapidly to 99% for the 16 to 20 years old age group but declined slightly for the oldest age group. The degree of seropositivity, which semi-quantitatively reflect the anti-M. furfur specific IgG titre, did not show any significant difference among the gender and racial groups. On the other hand, there was a significant difference in the degree of seropositivity among the various age groups, with the 16 to 20 years old age group having the highest antibody titre and the extreme of age groups having the lower antibody titre.

Item Type:Journal
Additional Information:This project was funded by a research grant (IMU 019/2002) from the International Medical University. We thank Dr T.S. Soo-Hoo and Miss L.S. Na, Department of Medical Microbiology, University of Malaya Medical Centre, Kuala Lumpur, for their kind guidance and assistance in the early isolation work of Malassezia furfur.
Keywords:Malassezia furfur, seroprevalence
Subjects:R Medicine, Dentistry, Pharmacy, Nursing
ID Code:1813

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