Mantle cell lymphoma – a clinicopathological study of 13 cases
Basu, Debdatta, and Yaranal, Parasappa J., and Kalyan, Koti, and Soundararaghavan, Jayanthi, (2005) Mantle cell lymphoma – a clinicopathological study of 13 cases. Malaysian Journal of Pathology, 27 (1). pp. 17-22. ISSN 0126-8635 Official URL: http://www.mjpath.org.my/past_issue/MJP2005.1/04Mantle.pdf AffiliationsJawaharlal Institute of Postgraduate Medical Education and Research, India Jawaharlal Institute of Postgraduate Medical Education and Research, India Jawaharlal Institute of Postgraduate Medical Education and Research, India Jawaharlal Institute of Postgraduate Medical Education and Research, India AbstractMantle cell lymphoma is an uncommon non-Hodgkin’s lymphoma. In a period of four years, 13 cases of mantle cell lymphoma were diagnosed in our department, comprising 3.1% of all non-Hodgkin’s lymphoma diagnosed. The mean age of presentation was 52 years with a slight male preponderance. The disease was nodal in twelve and extra-nodal in tonsil in one. Five patients had bone marrow involvement. Five cases showed a nodular pattern on lymph node biopsy while the remaining eight had a diffuse pattern. Immunophenotyping showed positivity for CD20 and cyclin D1. Despite certain morphological similarity to other low-grade lymphomas, mantle cell lymphoma has a characteristic appearance of its own. It is more aggressive than other low-rade lymphomas and hence needs to be accurately diagnosed. Repository Staff Only: item control page
|