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An In Vitro Study On The Anti-Adherence Properties Of Mouthrinses Containing Chlorhexidene Gluconate And Hexitidine

Fathilah A.R., and Othman Y., and Rahim Z.H.A., (1999) An In Vitro Study On The Anti-Adherence Properties Of Mouthrinses Containing Chlorhexidene Gluconate And Hexitidine. Annals of Dentistry, 6 (1). pp. 17-20. ISSN 0128-7532

Full text not available from this repository.

Official URL: http://ejum.fsktm.um.edu.my/ArticleInformation.aspx?ArticleID=460

Affiliations

University of Malaya. Faculty of Dentistry. Dept. of Oral Biology
University of Malaya. Institute of Biological Sciences
University of Malaya. Faculty of Dentistry. Dept. of Oral Biology

Abstract

Chlorhexidine gluconate and hexitidine have been used in many oral health care products as antiplaque and antigingivitis agents. Based on the clinical observations and the plaque and gingivitis scores, chlorhexidine gluconate has been reported to be a better agent. In this study, the anti-adherence properties of chlorhexidine gluconate and hexitidine on individual bacteria strains isolated from a 3-hour plaque (Streptococcus sanguis, Streptococcus mitis 1 and Actinomyces sp.) and on a whole 6-hour plaque culture were determined and compared. The study showed that chlorhexidine gluconate inhibited almost 100 % the adherence of the individual bacteria strains and 87.7 % the adherence of a whole 6-hour plaque culture to the saliva-coated glass surface. Hexitidine appeared to be more selective in its effect. It was shown to inhibit the adherence of S. sanguis and Actinomyces sp. to saliva-coated glass surface by 86.5 % and 51.4 % respectively. Its effect on the S. mitis 1 strains is comparable to that of a whole 6-hour plaque culture where inhibition to adherence were less than 4 % for both.

Item Type:Journal
Keywords:Chlorhexidine gluconate; hexitidine;adherence; affinity; anti-adherence
Subjects:R Medicine, Dentistry, Pharmacy, Nursing
ID Code:2083

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