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Langerhans Cell Histiocytosis: A Case Report And Update On Treatment Modalities

Hanafiah F. (Firdaus Hanapiah), and Windan T.M. (Tun Muzamal Windan), and Saeed, B.M.M., and Rahman R.A. (Rusdi Abdul Rahman), (1996) Langerhans Cell Histiocytosis: A Case Report And Update On Treatment Modalities. Annals of Dentistry, 3 (1). pp. 47-50. ISSN 0128-7532

Full text not available from this repository.

Official URL: http://ejum.fsktm.um.edu.my/ArticleInformation.aspx?ArticleID=506

Affiliations

University of Malaya. Faculty of Dentistry. Dept. of Oral and Maxillofacial Surgery
Royal London Hospital
University of Malaya. Faculty of Dentistry. Dept. of Oral and Maxillofacial Surgery

Abstract

Various treatment modalities exist for Langerhans cell histiocytosis(LCH) due to its uncertain aetiology.. LCH patients are clinically divided into a single and multisystem group and each group warrants a different approach to treatment. However, histologically, CD Ia antigen and Birbeck's granules have been implicated in both types of the disease. This article therefore describes clinical presentations of different forms of the disease and the treatments contrived for them. The single system group is treated conservatively with either curettage of the localised lesion, intralesional steroid injection or in some cases radiotherapy. For the multisystem group, treatment consists af chemotherapeutic agents as either a single or combination therapy.

Item Type:Journal
Keywords:Langerhans cell histiocytosis, Letterer-Siwedisease, Birbeck's
Subjects:R Medicine, Dentistry, Pharmacy, Nursing
ID Code:2145

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