Anti-inflammatory Properties of Mitragyna Speciosa Extract
Raja Aziddin R.E., and Mustafa M.R., and Mohamed Z., and Mohd. M.A., (2005) Anti-inflammatory Properties of Mitragyna Speciosa Extract. Malaysian Journal of Science, 24 (1). pp. 191-194. ISSN 13943065
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Official URL: http://www.ejurn.fsktm.um.edu.my/
University of Malaya, Faculty of Medicine, Dept. of Pharmacology, Kuala Lumpur, Malaysia
The anti-inflammatory property of the alkaloid extract from the leaves of Mitragyna speciosa was evaluated on the basis of the inhibitory effect of the extract on carrageenan-induced hind paw edema in rat. This extract when administered by intra peritoneal injection at a concentration of 50 mg/kg produced almost 100% inhibition of the carrageenan-induced paw edema 1 hour after administration. The inhibition was maintained at about 60%, 7 hours after administration. These findings suggest that the alkaloid extracts of the leaves of Mitragyna speciosa possess potent anti-inflammatory properties.
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