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Inhibition of Newcastle Disease Virus Propagation In Vero Cells By a Recombinant Bacteriophage And A Synthetic Peptide

Lee, Kheng Ji, and Eshaghi, Majid, and Khatijah Yusof, and Tan, Wen Siang, (2005) Inhibition of Newcastle Disease Virus Propagation In Vero Cells By a Recombinant Bacteriophage And A Synthetic Peptide. Malaysian Journal of Biochemistry and Molecular Biology, 11 (1). pp. 20-23. ISSN ISSN 1511-2616

Full text not available from this repository.

Official URL: http://ejum.fsktm.um.edu.my/ArticleInformation.aspx?ArticleID=618

Affiliations

Universiti Putra Malaysia. Faculty of Biotechnology and Biomolecular Sciences. Dept. of Microbiology
Universiti Putra Malaysia. Faculty of Biotechnology and Biomolecular Sciences. Dept. of Microbiology
Universiti Putra Malaysia. Institute of Bioscience
Universiti Putra Malaysia. Institute of Bioscience

Abstract

A recombinant filamentous phage bearing the peptide sequence CTLTTKLYC has been shown to interact tightly with Newcastle disease virus (NDV). The peptide, either alone or in the phage associated form, inhibited the hemolytic activity of the virus and also its propagation in embryonated chicken eggs. Here, we demonstrate that phage bearing the peptide sequence CTLTTKLYC and a synthetic peptide derived from the sequence inhibit the infection of Vero cells by NDV.

Item Type:Journal
Additional Information:This study was supported by the IRPA grant 01-02-04-003 BTK/ER/006 from the Ministry of Science, Technology and Innovation, Malaysia.
Keywords:Filamentous phage, peptide, inhibitory activities, cell culture
Subjects:Q Science, Computer Science
R Medicine, Dentistry, Pharmacy, Nursing
ID Code:2271

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