Author, Subjects, Keywords

Cited Author

 

 
   » By Author or Editor
 » Browse Author by Alphabet
 » By Journal
 » By Subjects
 » Malaysian Journals
 » By Type
 » By Year
 » By Latest Additions
 
 
   » By Author
 » Top 20 Authors
 » Top 20 Article
 » Top Journal Cited
 » Top Article Cited
 » Journal Citation Statistics
 » Usage Since Sept 2007


 
 
 

Login | Create Account

Noise Exposure Effect On Testicular Histology, Morphology And On Male Steroidogenic Hormone

Swami, Chandralekha G. , and Ramanathan, Jeganathan , and Jeganath.C, Charan , (2007) Noise Exposure Effect On Testicular Histology, Morphology And On Male Steroidogenic Hormone. Malaysian Journal of Medical Sciences, 14 (2). pp. 28-35. ISSN 1394195X

[img]
Preview
PDF - Requires a PDF viewer such as GSview, Xpdf or Adobe Acrobat Reader
1714Kb

Official URL: http://www.medic.usm.my/publication/mjms/our_journal/mjms_july2007/

Affiliations

Universiti Sains Malaysia, School of Medical Sciences, Dept. of Anatomy
Ragas Dental College, India, Dept. of Anatomy
Sri Ramachandra Medical College and Research Institute (Deemed University) India

Abstract

The noise stress, after it passes through the hearing apparatus, not only affects the auditory apparatus but also other body functions. The alterations in the levels of cortical hormone, adrenocorticosterone, nor-epinephrine hormone (which are primarily considered as stress hormones) on follicular stimulating hormone, testosterone, and lutinizing hormone were reported in relation with stress. Male albino rats weighing 200 to 250 grams were exposed to 100 dB of noise for one hour and three hours in acute group and daily one hour exposure for 60 day, and 90 day in chronic group. The serum testosterone levels were measured in these animals. There was significant reduction in serum testosterone levels and this was similar with earlier reports.The tissues were collected for light and confocal microscopic study. 100dB of traffic noise exposure of varying duration had definite permanent effect on testicular histology and morphology and on the male sex hormone . The adaptation mechanism was noticed at the hormonal level only but the structural changes noticed were definite and permanent. The agglutinated dead sperms revealed the possibility of infertily when chronically exposed to noise stress.

Item Type:Journal
Keywords:Noise Stress, Spermatogenesis¸ Sex Hormone
Subjects:R Medicine, Dentistry, Pharmacy, Nursing
ID Code:3603

1. Collins, (1995).Endocrine dysfunction.

2. Clark DA, Banwatt D, Chaouat G.Stress triggered abortion in mice prevented by alloimmunization. Am.J Reprod. Immunol.1993; 29:141-147.

3. Cosa, M., and Cosa, G. Annoyance, disturbance and damage caused by noise and vibration”. Ann lg 1989; 1: 133-156.

4. Nawrot PS, Cook RO, Hamm CW. Embryotoxicity of broadband and high frequency noise in the CD-1 mouse. J Toxicol Environ ealth.1981; 8: 151-157

5. Prabhakaran, K., Suthanthirarajan, N. And Namasivayam, A.Biochemical changes in acute noise stress in rats. Indian J. Phyriol. Pharma. Co.1988; 32: 100-104.

6. Armario, A. and Castellanos, J.M. Effects of noise stress on testosterone secretion in mice. IRCS. Med Sci.1984; 12: 208-210.

7. Faldikova L, Diblikova I, Canderle J, Zraly Z, Veznik Z, Sulcova A. Effect of nutrition,social factors and chronic stress on the mouse Leydig cell testosterone production. Vet.Med-Czech. 2001; 46: 160-168.

8. Dong Q, Salva A, Sottas CM, Niu E, Holmes M, Hardy MP. Rapid glucocorticoid mediation of suppressed testosterone biosynthesis in male mice subjected to immobilization stress. : J Androl. 2004; 25: 973-981

9. Armario, A., Campany L., Lopez–Calderon A. Pituitary – gonadal function in adult male rats subjected to chronic water restriction. J. Androl.1987; 8: 1-6

10. De Boer, S.F., Vander Gugten, J., and Slangen J.L. Plasma corticosterone and Catecholmine content induced by low doses of eltamethrine in rats. Toxicology.1988; 263-270.

11. Gopalakrishnan K,Gill-Sharma MK, Balasinor N, Padwal V, D’Souza S, Parte P, et al. Tamoxifen-induced light and electron microscopic changes in rat testicular morphology and serum hormonal profile of reproduvtive hormones. Contraception. 1998; 57: 261-269.

12. Hiroshi Yazawa, Isoji Sasagawa\l “FN1” \t “_blank” 1, Manabu Ishigooka and Teruhiro Nakada.Effect of immobilization stress on testicular germ cell apoptosis in rats. Human Reproduction.1999; 14: 1806-1810.

13. Sasagawa I, Yazawa H, Suzuki Y, Nakada T. Arch Androl. Stress and testicular germ cell apoptosis. 2001; 47:

14. Murthy NV, Wray SR, Melville GN, Wynter HH, Ram NV, Haran NV.Testicular function in rats following immobilization stress. Int J Gynaecol Obstet 1988;26:297-99.

15. Kobegenova, L.s., Kvanysh bekova, G.A. and Tulegeno, B. Levels of cortico steroids in laxity goats under stress. u. Akael. Nauk. Ka2. Ssr. Sor. Biol. 1985; 4:75-77.

16. Yu C, Yao Y, Yang Y, Li D.Changes of rat testicular germ cell apoptosis after high power microwave radiation., Zhonghua Nan Ke Xue. 2004; 10: 407-1

17. Lue Y, Hikim AP, Wang C, Im M, Leung A, Swerdloff RS.Testicular heat exposure enhances the suppression of spermatogenesis by testosterone in rats: the “twohit” approach to male contraceptive development. Endocrinology. 2000; 141: 1414-1424.

18. Sailer BL, SarkarB , Sarkar LJ, Bjordahl JA, Jost LK, Evenson DP.Effects of heat stress on mouse testicular cells and sperm chromatin structure. J Androl. 1997; 18: 294-301.

19. Animal ethics Committee, Kelantan. Ref : PPSG/07(A)/044, 2 Disember 2002.

20. Noguchi.J,m.Yoshida,H.ikadai,T.Imamichi,G. Watanabe. Age-related changes in blood concentrations of FSH,LH and testosterone and testicular morphology in a new rat sterile mutant with heredity aspermia. J Reprod. Fert. 1993; 97: 433-439.

21. Amanda Beardsel and Beardsley A, O’Donnell L. Characterization of normal spermiation and spermiation failure induced by hormone suppression in adult rats. Biol Reprod. 2003; 68: 1299-1307

22. Mylchreest E, Sar M, Wallace DG, Foster PM. Fetal testosterone insufficiency and abnormal proliferation of Leydig cells and gonocytes in rats exposed to di (nbutyl) phthalate. Reprod Toxicol. 2002; 16:19-28

23. Pellegrini, A., Soldani, P., Gesi, M., Lenzi, P., Martin, F.Diazepam reduced ultra structural changes induced by noise stress in rats adrenal gland. Journal of sub microscopic cytology and pathology. 1998; 30: 385- 391

24. Orr TE,Taylor MF, Bhattacharyya AK, Collins DC, Mann DR. Acute immobilization stress disrupts testicular steroidogenesis in adult male rats by inhibiting the activities of 17 alpha-hydroxylase and 17,20-lyase without affecting the binding of LH/hCG receptors. Androl. 1994; 15: 302-308

25. Bambino, T. and Hsueh, A.Direct inhibitory effect of glucocorticoids upon testicular luteinizing hormone receptors and steroidogenesis in vivo and in vitro. Endocrinology.1981; 108, 2142–2148

26. Srivastava, R.K., Taylor, M.F. and Mann, D.R.Effect of immobilization stress on plasma luteinizing hormone, testosterone, and corticosterone concentrations and on 3ß-hydroxysteroid dehydrogenese activity in the testes of adult rats. Proc. Soc. Exp. Biol. Med.1993; 204: 231–235.

27. Yazawa H, Sasagawa I,Ishigooka M, Nakada T Effect of immobilization stress on testicular germ cell apoptosis in rats. Hum Reprod. 14: 1806-1810

28. Sapolsky, R.M. (1985) Stress-induced suppression of testicular function in the wild baboon. Role of glucocorticoids. Endocrinology. 1999; 116: 2273– 2278.

29 . Chandralekha G, The effect of noise induced stress on the male reproductive endocrine glands of Albino rats,Ph.D thesis, 2002. Dr. M.G.R. Medical University and Research Chennai.

30. Ozguner M , Koyu A, Cesur G, Ural M, Ozguner F, Gokcimen A, Delibas N. Biological and morphological effects on the reproductive orgrans of rats after Exposure to electromagnetic field. Saudi Med J. 2005; 26: 405-410.

31. Oakes DJ, Webstrer Ws, Brown-Woodman Pd, Ritchie HE. Testicular changes induced by chronic exposure to the herbicide formulatin, Tordon 75D(2,4- dichorophenoxyacetic acid and picloram) in rats. Reprod Toxicol. 2002; 16: 281-289

32. Ogale, S.B. ‘Noise overload’ Health and Nutriens.1999; Oct; 85-89

Repository Staff Only: item control page