Author, Subjects, Keywords

Cited Author

 
 
   » By Author or Editor
 » Browse Author by Alphabet
 » By Journal
 » By Subjects
 » Malaysian Journals
 » By Type
 » By Year
 » By Latest Additions
 
 
   » By Author
 » Top 20 Authors
 » Top 20 Article
 » Top Journal Cited
 » Top Article Cited
 » Journal Citation Statistics
 » Usage Since Sept 2007


 
 
 

Login | Create Account

Alpha-l-antitrypsin Deficiency in Babies with Prolonged Jaundice

Zakiah I., and Mohd. Zaini A.R., and Jamilah B Md, and Zawiah A., (1992) Alpha-l-antitrypsin Deficiency in Babies with Prolonged Jaundice. Malaysian Journal of Pathology, 14 (2). pp. 91-94. ISSN 0126-8635

Full text not available from this repository.

Official URL: http://www.mjpath.org.my/past_issue/MJP1992.2/alpha1%20antitrypsin%20deficiency%20in%20babies%20with%20prolonged%20jaundice.pdf

Affiliations

Institute for Medical Research Malaysia. Dept. of Biochemistry["lib/metafield:join_corp_creators" not defined]General Hospital, Kuala Lumpur. Dept. of Laboratory Services["lib/metafield:join_corp_creators" not defined]Institute for Medical Research Malaysia. Dept. of Biochemistry["lib/metafield:join_corp_creators" not defined]Institute for Medical ResearchMalaysia. Dept. of Biochemistry

Abstract

Over a three-year-period, 310 babies with prolonged jaundice admitted to GHKL were studied, to determine the incidence of alpha-l-antitrypsin deficiency as a cause of the problem. Ninety-two babies (29.7%) were found to be alpha-l-antitrypsin deficient. The percentage incidence was found to be highest in Indians (33.3%), followed by Malays (31.9%) and Chinese (26.7%). There was a male preponderance with a M:F ratio of 1.6: 1. Most of these babies presented at the hospital at the age of more than two weeks but less than one month. Apart from the problem of prolonged jaundice
and alpha-l-antitrypsin deficiency, 2 had associated bleeding problems, 1 I associated infections and 3 respiratory problems. Two babies had clinical features of Down's syndrome, 2 had G6PD deficiency and 1 had congenital hypothyroidism. AST, ALT and ALPO, were high in 20, 26 and 3
babies respectively.

Item Type:Journal
Additional Information:This note was added by the search_and_modify.pl script.
Keywords:Alpha-l-antitrypsin deficiency, neonatal jaundice.
Subjects:R Medicine, Dentistry, Pharmacy, Nursing
ID Code:3703

1. Ishenvood DM, Hetcher KA. Neonatal jaundice: investigation and monitoring. Ann Clin Biochem 1985; 22: 109-28.

2. Crystal RC. Alpha-l-antitrypsin deficiency, emphysema and liver diseases. Genetic basis and strategies for therapy. J Clin Invest 1990; 85: 1343-52.

3. Malfalt R, Gorus F, Sevens C. Electrophoresis of serum protein to detect alpha-l-antitrypsin deficiency: five illustrative cases. Clin Chem 1985; 3 l(8): 1397-9.

4. Laurel1 CB. Electroimmunoassay. Scan J Clin Lab Invest 1972; 29 (supp. 124): 21-37.

5. Sveger T. Liver disease in alpha- l-antitrypsin deficiency detected by screening of 200,000 infants. N Engl J Med 1976; 294: 1316-21.

6. Ledley FD, Woo SLC. Molecular basis of alpha-lantitrypsin deficiency and its potential therapy by gene transfer. J Inherited Metab Dis 1986; 9 (supp.1): 85-91.

7. Cox DW, Mansfield T. Prenatal diagnosis of alpha-

I-antitrypsin deficiency and estimates of fetal risk for disease. J Med Gen 1987; 24: 52-9.

Repository Staff Only: item control page
 
 
 
 
 
 
© Copyright 2007 MyAIS Faculty of Computer Science and Information Technology, University of Malaya – All Rights Reserved. Malaysian Abstracting and Indexing System is powered by EPrints 3 which is developed by the School of Electronics and Computer Science at the University of Southampton. More information and software credits.