Author, Subjects, Keywords

Cited Author

 

 
   » By Author or Editor
 » Browse Author by Alphabet
 » By Journal
 » By Subjects
 » By Affiliations
 » By Type
 » By Year
 » By Latest Additions
 
 
   » By Author
 » Top 20 Authors
 » Top 20 Article
 » Top Journal Cited
 » Top Article Cited
 » Journal Citation Statistics
 » Usage Since Sept 2007


 
 
 

Login | Create Account

Summarizing Research Findings: Systematic Review And Meta-Analysis

Wong, Li Ping, (2007) Summarizing Research Findings: Systematic Review And Meta-Analysis. Malaysian Family Physicians , 2 (1). pp. 8-12. ISSN 1985-2274

[img]
Preview
PDF - Requires a PDF viewer such as GSview, Xpdf or Adobe Acrobat Reader
142Kb

Official URL: http://www.ejournal.afpm.org.my/2007v2n1/pdf/Summarizing%20research%20findings_systematic%20review%20and%20meta-analysis.pdf

Affiliations

Universiti Malaya, Faculty of Medicine, Health Research Development Unit

Abstract

The explosion of biomedical publishing makes keeping up with the primary studies an impossible task. The often disparate, confusing and contradicting findings of individual studies makes healthcare professionals turn to review articles where knowledge has been collated and published in summaries. Narrative reviews lack rigorous, systematic and reproducible synthesis. In contrast, systematic reviews are conducted using systematic and explicit methods to identify, select and critically appraise relevant research, and to collect and analyse data from the studies that are included in the review. The final pathway for systematic review is a statistical summary of the results of primary studies, or meta-analysis. This article provides some guidelines to health care providers in understanding the key aspects of systematic review and meta-analysis. Steps involved in systematic review are discussed. The potential pitfall of meta-analysis was also explored.

Item Type:Journal
Keywords:Systematic Review, Meta-Analysis, biomedical literature
Subjects:R Medicine, Dentistry, Pharmacy, Nursing
ID Code:3912

1. MEDLINE fact sheet. [Web Document]. Bethesda, MD: National Library of Medicine. http://www.nlm.nih.gov/pubs/factsheets/medline.html. [Accessed on 12th March 2007]

2. Williamson JW, German PS, Weiss R, Skinner EA, and Bowes F. Health science information management and continuing education of physicians. A survey of U.S. primary care practitioners and their opinion leaders. Ann Intern Med. 1989;110(2):151-60

3. Hunt RE, Newman RG. Medical knowledge overload: a disturbing trend for physicians. Health Care Manage Rev. 1997; 22(1):70-5

4. Thacker SB. Meta-analysis: a qualitative approach to research integration. JAMA. 1988;259(11):1685-9

5. Oxman A, Guyatt GH, Cook D, Montori V, Guyatt GH, Rennie D. User’s Guides to the Medical Literature. A Manual for Evidence-based Clinical Practice. Chicago, Ill: AMA Press; 2005. pp.155-73.

6. Egger M, Davey Smith G, O’Rourke K. Rational, potentials and promise of systematic reviews. In: Egger M, Davy Smith G, Altman DG (eds). Systematic Reviews in Health Care: Meta-Analysis in Context. London: BMJ Books. 2001, pp. 23-42

7. Sutton AJ, Abrams KR, Jones DR, Sheldon TA, Song F. Systematic reviews of trials and other studies. Health Technol Assess. 1998;2(19):1- 272

8. Ferrer RL. Graphical methods for detecting bias in metaanalysis. Fam Med. 1998;30(8):579-83

9. Eysenck HJ. An exercise in mega-silliness. Am Psychol. 1978;33:517

10. Boden WE. Meta-analysis in clinical trials reporting: Has a tool become a weapon? Am J Cardiol. 1992;69(6):681-6

11. Oakes M. Statistical inference: a commentary for the social and behavioral science. Chichester: John Wiley & Sons, 1986

12. Bailar JC. The promise and problems of meta-analysis. N Engl J Med. 1997;337(8):559-61

13. Nurmohamed MT, Rosendaal FR, Bueller HR, et al. Low molecular-weight heparin versus standard heparin in general and orthopaedic surgery: a meta-analysis. Lancet 1992;340:152-6

14. Leizorovicz A, Haugh MC, Chapuis FR, Samama MM, Boissel JP. Low molecular-weight heparin in prevention of perioperative thrombosis. BMJ. 1992;305:913-20

15. Egger M, Davey Smith G, Sterne JAC. Uses and abuses of meta-analysis. Clin Med. 2001;1(6):478-84

16. Chalmers I, Altman DG. Systematic reviews. London, BMJ Press, 1995

17. Mulrow CD. Rationale for systematic reviews. BMJ. 1994;309:597-9

Repository Staff Only: item control page