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A Retrospective Review Comparing the Use of Gonal-F and Metrodin-HP for In-Vitro Fertilisation (IVF)

Colin, Lee, and Mak, F.S., and Keith, J., and Welsh, D., and Paulina, Yapp, and Rachel, Chin, (2003) A Retrospective Review Comparing the Use of Gonal-F and Metrodin-HP for In-Vitro Fertilisation (IVF). Medical Journal of Malaysia, 58 (1). pp. 94-98. ISSN 0300-5283

Full text not available from this repository.

Affiliations

Damansara Fertitity Centre, Petaling Jaya
Damansara Fertitity Centre, Petaling Jaya
Damansara Fertitity Centre, Petaling Jaya
Damansara Fertitity Centre, Petaling Jaya
Damansara Fertitity Centre, Petaling Jaya
Damansara Fertitity Centre, Petaling Jaya

Abstract

All cycles of IVF with pituitary down-regulation (n=57) done at the Damansara Fertility Centre in the year 2000 were studied. All the 57 patients had controlled ovarian hyperstimulation, either using Metrodin HP (n=27) or Gonal-F (n=30). Of these, 53 patients reached oocyte pick-up, 26 patients in Metrodin HP group and 27 patients in Gonal-F group. Gonal-F resulted in a higher clinical pregnancy rate of 66.6% compared to Metrodin HP 38.5% (p<0.05). The live birth rate tends to be higher in Gonal- F group (40.7%) compared to Metrodin HP (30.8%), (p>0.05).

Item Type:Journal
Keywords:In-Vitro fertilization, Metrodin HP (uFSH-HP), Gonal-F(rFSH), Clinical pregnancy rate, Live birth rate
Subjects:R Medicine, Dentistry, Pharmacy, Nursing
ID Code:6216

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4. Bergh C, Howles C, Borg K, et al. Recombinant human follicle stimulating hormone (r-hFSH; Gonal-F) versus highly purified urinary FSH (Metrodin HP): results of a randomized comparative study in women undergoing assisted reproductive techniques. Hum Reprod 1997; 12: 2133-9

5. Daya S, Gunby J et al. Recombinant versus urinary follicle stimulation hormone for ovarian stimulation in assisted reproduction. Hum Reprod 1999; 14: 2207-15

6. Cohn Lee, John Keith, Low AL, Wong HY, Chong WA, Keling J et al. Results of GIFT at a private Fertility Centre. XVIth Asian & Oceanic Congress of Obstetrics and Gynaecology proceedings, June 1998.

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