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The Prognostic Value of C-Reactive Protein (CRP) Levels in Patients with Acute Ischaemic Stroke

Hamidon B.B., and Sapiah S., and Nawawi H., and Raymond, A.A., (2004) The Prognostic Value of C-Reactive Protein (CRP) Levels in Patients with Acute Ischaemic Stroke. Medical Journal of Malaysia, 59 (5). pp. 631-637. ISSN 0300-5283

Full text not available from this repository.

Affiliations

University Kebangsaan Malaysia. Faculty of Medicine. Dept. of Medicine.
University Kebangsaan Malaysia. Faculty of Medicine. Dept. of Medicine.
University Kebangsaan Malaysia. Faculty of Medicine. Dept. of Pathology.
University Kebangsaan Malaysia. Faculty of Medicine. Dept. of Pathology.

Abstract

Increasing evidence suggests that inflammation plays an important role in the development of both cardiovascular and for cerebrovascular events. Recently C-reactive protein (CRP) levels have been reported to be a prognostic factor for cerebrovascular and cardiovascular events. The main objective of the study was to evaluate the prognostic value of CRP levels in a first ever ischaemic stroke at one month. All ischaemic stroke patients who were admitted to Hospital Universiti Kebangsaan Malaysia (HUKM) between May 2002 and July 2002 were eligible for the study. CRP levels were taken within 72 hours after an acute ischaemic stroke. The functional ability was assessed using the Barthel Index (BI) after one month of stroke. During the study period 84 patients were admitted to HUKM with the diagnosis of ischaemic stroke; 49 patients were enrolled and 35 were excluded. Twenty-nine patients (59.2%) had elevated CRP levels (median 1.64 ± 3.07 mg/dL, range 0.06 to 16.21 mg/dL). Elevated CRP levels were found to be a predictor of severe functional disability (BI<5) and were also associated with larger infarcts. In conclusion, elevated CRP levels are associated with poorer functional outcome and predict a larger infarct size.

Item Type:Journal
Keywords:C-reactive protein, Acute ischaemic stroke
Subjects:R Medicine, Dentistry, Pharmacy, Nursing
ID Code:6439

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