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Medication Compliance Among Renal Transplant Patients: A Hospital Kuala Lumpur Experience

Liu, W.J., and Zaki, M., (2004) Medication Compliance Among Renal Transplant Patients: A Hospital Kuala Lumpur Experience. Medical Journal of Malaysia, 59 (5). pp. 649-656. ISSN 0300-5283

Full text not available from this repository.

Affiliations

Hospital Kuala Lumpur. Dept. of Nephrology.
Hospital Kuala Lumpur. Dept. of Nephrology.

Abstract

This survey aims to identify prevalence, reasons and predictors of noncompliance among renal transplant patients followed up in Hospital Kuala Lumpur (HKL). All adult renal transplant patients who were a least 6 months post transplant were recruited from 10/2001 till 5/2002. Patients who consented were interviewed by a medical doctor or research assistant based on questionnaire. Noncompliers were defined as those who missed or self adjusted any dose of immunosuppressant within the preceding 4 weeks. Inter-rater agreement was assessed prior by Kappa (K) scores and they were acceptable. Out of 304 patients, 246 patients volunteered; of whom 144 (58.5%) were males. Twenty-one (9.3%) were noncompliers. Reasons for noncompliance included forgetfulness (n=8), financial constraints (n=1), fear of rejection (n=1), side effects (n=9), decision not to take (n=6), difficulty in breaking medication into correct dosages (n=1). Significant predictors of noncompliance were longer duration of transplant, noncompliance to other drugs, regular use of nonprescription drugs; the lack of symptoms of fat facial cheeks and infection. Surveillance for noncompliance should not be relaxed as its predictors are diverse and persistent, especially in those who are at high risks.

Item Type:Journal
Keywords:Compliance, Renal transplant
Subjects:R Medicine, Dentistry, Pharmacy, Nursing
ID Code:6441

1. Laederach-Hofmann K, Bunzel B. Noncompliance in organ transplant recipients: a literature review. Gen Hosp Psychiatry 2000; 22: 412-24.

2. Chisholm MA, Vollenweider LJ, Mulloy LL et al. Renal transplant patient compliance with free immunosuppressive medications. Transplantation 2000; 70: 1240—244.

3. Raiz LR, Kilty KM, Henry ML, Ferguson RM. Medication compliance following renal transplantation. Transplantation 1999; 68: 51—55.

4. Monaco AP, Burke JF Jr, Ferguson RM et al. Current thinking on chronic renal allograft rejection: issues, concerns, and recommendations from a 1997 roundtable discussion. Am J Kidney Dis 1999; 33: 150-60.

5. De Geest S, Vanhaecke J. Methodological issues in transplant compliance research. Transplant Proc 1999; 31: 81S—83S.

6. Didlake RH, Dreyfus K, Kerman RH, et al. Patient noncompliance : a major cause of late graft failure in cyclosporine-treated renal transplants. Transplant Proc 1988; 20 (3) Suppl 3: 63-69.

7. Lim TO, Lim V. Seventh report of the Malaysian Dialysis and Transplant Registry, 1999.

8. Greenstein S, Siegal B. Compliance and noncompliance in patients with a functioning renal transplant: multicentre study. Transplantation 1998; 66 (12): 1718—726.

9. Sketris I, Waite N, Grobler K, et al. Factors affecting compliance with cyclosporine in adult renal transplant patients. Transplant Proc 1994; 26 (5): 2538-541.

10. Kiley DJ, Lam CS, Pollak R. A study of treatment compliance following kidney transplantation. Transplantation 1993; 55(1): 51-56.

11. Schweizer RT, Rovelli M, Palmeri D et al. Noncompliance in organ transplant recipients. Transplantation 1990; 49(2): 374-77.

12. Rovelli M, Palmeri D, Vossler E et al. Noncompliance in organ transplant recipients. Transplantation Proc 1989; 21(1): 833-34.

13. Butkus DE, Meydrech EF, Raju SS. Racial differences in the survival of cadaveric renal allografts. N Eng J Med 1992; 327: 840-45.

14. Kory L. Nonadherence to immunosuppressive medications: A pilot survey of members of the Transplant Recipients International Organization. Transplant Proc 1999; 31(Supp 4A), 14S-15S.

15. Hathaway DK, Combs C, De Geest S, Stergachis A, Moore LW. Patient compliance in Transplantation : A report on the perceptions of transplant clinicians. Transplant Proc 1999; 31 (Supp 4A), 10S-13S.

16. Cramer JA. Practical issues in medication compliance. Transplant Proc 1999; 31(Supp 4A), 7S-9S.

17. Dew MA, Roth LH, Thompson ME, Kormos RL, Griffith BP. Medical compliance and its predictors in the first year after heart transplantation. J Heart Lung Transplant 1996; 15: 631-45.

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