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Seroepidemiology of Toxoplasmosis Among HIV-Infected Patients and Healthy Blood Donors

Nissapatorn, V., and Kamarulzaman A., and Init, I., and Tan, L.H., and Rohela M., and Norliza A., and Chan, L.L., and Latt, H.M., and Khairul Anuar A., and Quek, K.F., (2002) Seroepidemiology of Toxoplasmosis Among HIV-Infected Patients and Healthy Blood Donors. Medical Journal of Malaysia, 57 (3). pp. 304-310. ISSN 0300-5283

Full text not available from this repository.

Affiliations

University Malaya Medical Centre. Dept. of Parasitology.
University Malaya Medical Centre. Dept. of Medicine.
University Malaya Medical Centre. Dept. of Parasitology.
University Malaya Medical Centre. Dept. of Medicine.
University Malaya Medical Centre. Dept. of Parasitology.
University Malaya Medical Centre. Dept. of Medicine.
University Malaya Medical Centre. Dept. of Parasitology.
University Malaya Medical Centre. Dept. of Social and Preventive Medicine.
University Malaya Medical Centre. Dept. of Parasitology.
University Malaya Medical Centre.Health Research Development Unit.

Abstract

A cross-sectional study was carried out in University of Malaya Medical Centre, Kuala Lumpur. Blood samples from 100 HIV-infected patients and 203 Healthy Blood Donors (HBD) were collected and anti- $Toxoplasma$ antibodies were detected by using conventional ELISA. The seroprevalence of toxoplasmosis in HIV/AIDS and Healthy Blood Donors were found to be 21% and 28.1% respectively. There was no significant association between the seroprevalence of toxoplasmosis and various possible risk factors i.e. contact with cat, consumption of undercooked meat and history of blood transfusion in both groups. No significant differences between $Toxoplasma$ seroprevalence in HIV/AIDS and Health Blood Donors in association with presence of single or multiple risk factors were found. The mean CD4 count among HIV/AIDS patients in this study was 202.23 cell/cumm. There was no significant association between CD4 count and seropositivity for $Toxoplasma$ antibodies in HIV/AIDS patients.

Item Type:Journal
Keywords:HIV, Blood donors, Malaysia
Subjects:R Medicine, Dentistry, Pharmacy, Nursing
ID Code:7189

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7. Del Rio-Chiriboga, Orzechowski-Rallo A, Sanchez-Mejorada G. Toxoplasmosis of the central nervous system in Patients with AIDS in Mexico. Arch Med Res 1997; 28(4): 527-30.

8. Nissapatorn V. Seroprevalence of toxoplasmosis in HIV-infected patients in Chonburi Regional Hospital, Chonburi, Thailand. Thesis for M.C.T.M. degree. Faculty of Tropical Medicine, Mahidol University, Bangkok 1998. In press.

9. Luft BJ, Remington JS. AIDS commentary: toxoplasmic encephalitis. J Infect Dis 1988; 157: 1-6.

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11. Mark RW, Rita JR, Patrick EO. Cats and toxoplasmosis risk in HIV-infected adults. JAMA 1993; 269: 76-7.

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