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The Incidence of Malignant Infiltration in the Biopsy Tract of Osteosarcoma

Mohana R., and Faisham W.I., and Zulmi W., and Nawfar A.S., and Effat O., and Salzihan M.S., (2007) The Incidence of Malignant Infiltration in the Biopsy Tract of Osteosarcoma. Malaysian Orthopaedic Journal , 1 (2). pp. 7-10. ISSN 1985 2533

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Official URL: http://www.morthoj.org/2007v1n2/The_Incidence_of_Malignant_Infiltration_in_the_Biopsy_Tract_of_Osteosarcoma.pdf

Affiliations

Universiti Sains Malaysia. School of Medical Sciences. Dept. of Orthopaedics.
Universiti Sains Malaysia. School of Medical Sciences. Dept. of Orthopaedics.
Universiti Sains Malaysia. School of Medical Sciences. Dept. of Orthopaedics.
Universiti Sains Malaysia. School of Medical Sciences. Dept. of Orthopaedics
Universiti Sains Malaysia, School of Medical Sciences. Dept. of Pathology
Universiti Sains Malaysia, School of Medical Sciences. Dept. of Pathology

Abstract

Biopsy is a crucial step in the management of musculoskeletal sarcoma. The surgical approach to the biopsy site is important, as the tract must be removed en bloc with the tumour during limb sparing surgery so as to reduce the risk of local recurrence. The biopsy tracts of 26 osteosarcoma patients were evaluated histologically for
tumour infiltration. Horizontal sections of 1 mm thickness
with 2 cm radius from were evaluated from each excised biopsy tract. Five out of 26 cases (19.2%) showed positive tumour infiltration. One case (3.85%) had tumour infiltration in the pseudocapsule, two cases (7.69%) had tumour infiltration into the muscle and two other cases (7.69%) had tumour infiltration into the subcutaneous tissue. None had skin infiltration. We conclude that resection of the entire biopsy tract is indeed mandatory for surgical treatment of osteosarcoma.

Item Type:Journal
Additional Information:The study was funded by short term grant University Sains Malaysia 304/PPSP/6131385
Keywords:Biopsy tract, Osteosarcoma, Histopathology
Subjects:R Medicine, Dentistry, Pharmacy, Nursing
ID Code:7301

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