Author, Subjects, Keywords

Cited Author

 
 
   » By Author or Editor
 » Browse Author by Alphabet
 » By Journal
 » By Subjects
 » Malaysian Journals
 » By Type
 » By Year
 » By Latest Additions
 
 
   » By Author
 » Top 20 Authors
 » Top 20 Article
 » Top Journal Cited
 » Top Article Cited
 » Journal Citation Statistics
 » Usage Since Sept 2007


 
 
 

Login | Create Account

Sourcing Different Neuro-Progenitor Cell for the Use of Nerve Construct

Yazid A.G.M., and Anuar A., and Onhmar H.T.W.E., and Ng, A.M.H., and Ruszymah B.H.I., and Amaramalar, S.N., (2008) Sourcing Different Neuro-Progenitor Cell for the Use of Nerve Construct. Medical Journal of Malaysia, 63 (Supplement A). pp. 113-114. ISSN 0300-5283

Full text not available from this repository.

Affiliations

Universiti Kebangsaan Malaysia. Faculty of Medicine. Dept. of Orthopedic & Universiti Kebangsaan Malaysia Medical Centre. Tissue Engineering Centre.
Universiti Kebangsaan Malaysia. Faculty of Medicine. Dept. of Orthopedic.
Universiti Kebangsaan Malaysia. Faculty of Medicine. Dept. of Orthopedic.
Universiti Kebangsaan Malaysia Medical Centre. Tissue Engineering Centre.
Universiti Kebangsaan Malaysia Medical Centre. Tissue Engineering Centre.
Universiti Kebangsaan Malaysia. Faculty of Medicine. Dept. of Orthopedic.

Abstract

Spinal cord, sciatic nerve, olfactory ensheathing cell and bone marrow derived mesenchymal stem cells were evaluated as an alternative source for tissue engineering of nerve conduit. All cell sources were cultured in alpha-MEM medium. Olfactory Ensheathing Cell (OEC) showed the best result with higher growth kinetic compared to the others. Spinal cord and sciatic nerve were positive for GFAP, OEC were positive for GFAP, Sloob and anti-cytokeratin 18 but negative for anti-Human Fibroblast.

Item Type:Journal
Additional Information:Previous study showed that cultured DEC can express a number of nerve growth factors such as NGF, BDNF and NT-3². It enhances proliferation and survival of immortalized DEC. We conclude that DEC was the best neuroprogenitor cell source compared to others being studied. More research on the characterization and functional properties are on the way.
Subjects:R Medicine, Dentistry, Pharmacy, Nursing
ID Code:7928

1. Komiyama T, et al. A novel technique to isolate adult Schwann cells for an artificial nerve conduit. J. Neuroscience Methods. 2003; 122: 195-200.

2. Woodhall E, et al. Cultured olfactory ensheathing cells express nerve growth factor, brain-derived neurotrophic factor, glial cell line-derived neurotrophic factor and their receptors. Molecular Brain Research. 2001; 88: 203-13.

3. Wu D, Shibuya S, Miyamoto O, Itano T, Yamamoto T. Increase of NG2-positive cells associated with radial glial following traumatic spinal cord injury in adult rats. J. Neurocytol. 2005; 34: 459-69.

4. Keilhoff G, Goihl A, Stang F, Wolf G, Fansa H. Peripheral nerve tissue engineering: autologous Schwann cells vs. transdifferentiated Mesenchymal stem cells. Tissue engineering. 2006; 12(6): 1415-65.

Repository Staff Only: item control page
 
 
 
 
 
 
© Copyright 2007 MyAIS Faculty of Computer Science and Information Technology, University of Malaya – All Rights Reserved. Malaysian Abstracting and Indexing System is powered by EPrints 3 which is developed by the School of Electronics and Computer Science at the University of Southampton. More information and software credits.