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Chemical Constituents And Bioactive Compunds Of Goniothalamus Tortilipetalus Hend (annonaceae)

Ropi Mukhtar M., and Khalijah Awang, and Mustafa M.R., and Norhanum A.W., and Ashril Y., and A. Hamid A. Hadi, and , (2000) Chemical Constituents And Bioactive Compunds Of Goniothalamus Tortilipetalus Hend (annonaceae). Malaysian Journal of Science, 19 (1). pp. 13-18. ISSN 13943065

Full text not available from this repository.

Affiliations

University of Malaya, Centre for Foundation Studies
University of Malaya, Faculty of Science, Dept. of Chemistry
University of Malaya, Faculty of Medicine, Dept. of Pharmacology
University of Malaya, Institute of Biological Sciences
University of Malaya, Faculty of Sports Science
University of Malaya, Faculty of Science, Dept. of Chemistry

Abstract

A Malaysian plant, Goniothalamus Tortilipetalus Hend (Annonaceae) was studied for its chemical constituents and biological activities. The stem bark of Goniothalamus Tortilipetalus, produced two isoquinolines namely discretamine (1) and liriodenine (2). The leaves yielded asimilobine (3), liriodenine (2) and Lanuginosine (4). In addition, non-alkaloidal aromatic compunds were also prified from the petroleum ether extract. THey were 6-styryl-2-pyrone (5) and goniothalamin (6). The pharmacological study revealed that 6-styryl-2=pyrone possesses a vasorelasant effect on rat aorta and it is cytotoxic to KB cells (ED50=48.5µg/ml). The Goniothalamus Tortilipetalus Hend was collected at Grik, Perak.

Item Type:Journal
Keywords:Alkaloid; Annonaceae; Cytotoxicity; Goniothalamus Tortilipetalus; Vasorelaxant effect, alkaloids; Aromatic compunds.
Subjects:Q Science, Computer Science
ID Code:807

1. Potier, P. (1989). The synthesis of navelbine prototype of a new serie of vinblastine derivatives, Seminar in Oncology 16, Suppl 4.

2. Belle, R.; Nepol, P.; David, B & Vercauteren, J. (1996). Phytochemistry. Submitted for publication.

3. Oulad, A.; Guillaume, D.; Belle, R.; David, B. & Anton, R. Phytochemistry accepted for publication.

4. Dunouau, C.; Belle, R., Oulad, A.; Anton, R. & David, B. (1996). J. Nat. Prod. Submitted for publication.

5. Oulad, A,; Dunouau, C.; Belle, R.; Anton, R. & David, B. (1996). J. Nat Prod. Submitted for publication.

6. Oulah, A.; David, B.; Charrouf, Z.; Belle, R. & Anton, R. (1996). Int. J. of Pharmacognosy to be published.

7. POrrat, J.L.; Lamaison, Gramain, J.C. & Remuson, R. (1982). Ann. Pharm. Fr. 40:451458.

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