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Screening of Antenatal Mothers and Prevention of Perinatal Group B Streptococcal Infection

Raj, M., and Razali N., and Sulaiman S., (2009) Screening of Antenatal Mothers and Prevention of Perinatal Group B Streptococcal Infection. Journal of the University of Malaya Medical Centre (JUMMEC), 12 (1). pp. 27-30. ISSN 1823-7339

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Official URL: http://jummec.um.edu.my

Affiliations

University of Malaya, Faculty of Medicine, Dept. of Obstetrics and Gynaecology
University of Malaya, Faculty of Medicine, Dept. of Obstetrics and Gynaecology
University of Malaya, Faculty of Medicine, Dept. of Obstetrics and Gynaecology

Abstract

The objectives of this study were: (1) to detect group B streptococcus (GBS) carriers among antenatal patients during pregnancy ( 35 to 37 weeks) in the University Malaya Medical Centre (UMMC), Kuala Lumpur, Malaysia, and (2) to give antibiotic prophylaxis during the intrapartum period for the GBS carrier patients. The aim is to prevent early onset of GBS infection in newborn. This pilot study was carried out from 1st July 2005 to 31st August 2005. It is a prospective study involving 56 pregnant women who were seen at the antenatal clinic in the UMMC between 35 to 37 weeks gestation. High vaginal swab and low vaginal together with endoanal swab were taken for culture and sensitivity. The antibiotic prophylaxis was started early in the intrapartum period for patients with positive culture for GBS. GBS was detected in 18 patients which contributes to about 32% of the study population. The proper choice of antibiotic is important in successful disease prevention.

Item Type:Journal
Keywords:Group B streptococcus , screening, pregnant women, Malaysia
Subjects:R Medicine, Dentistry, Pharmacy, Nursing
ID Code:8571

1. Fry, RM. Fatal infections by hemolytic streptococcus group B. Lancet 1938; 1: 199-201.

2. Eickhoff, T., Klein JO, Daly AK, Ingall D, Finland M. Neonatal sepsis and other infections due to group B beta-hemolytic streptococci. N Engl. J Med 1964; 271: 1221-1228.

3. McCracken GH. Group B streptococci: The new challenge in neonatal infections. J Pediatr 1973; 82: 703-706.

4. Benitez WE, Gould JB, Druzin ML. Antimicrobial prevention of early-onset group B streptococcal sepsis: Estimates of risk reduction based on a critical literature review. Pediatrics 1999; 103: 78.

5. Brozanski BS, Jones, JG, Krohn, MA, Sweet RL. Effect of a screening-based prevention policy on prevalence of early-onset group B streptococcal sepsis. Obstet Gynecol 2000; 95: 496-501.

6. Schuchat A, Wenger JD. Epidemiology of group B streptococcal disease: Risk factors, prevention strategies and vaccine development. Epidemiol Rev 1994; 16: 374-402.

7. Strus M, Pawlik D, Brzychczy-Wloch M et al. Group B streptococcus colonization of pregnant women and their obstetric and neonatal ward of the University Hospital in Krakow, Poland. J Med Microbiol 2009 Feb; 58 (Pt2): 228-233.

8. Centers for Disease Control and Prevention. Trends in perinatal group B streptococcal disease-United States, 2000-2006. MMWR Morb Mortal Wkly Rep 2009 Feb 13; 58(5):109-112.

9. de Cueto M, Sanchez MJ, Sampedro A, Miranda JA, Herruzo AJ, Rosa-Fraile M. Timing of intrapartum ampicillin and prevention of vertical transmission of group B streptococcus. Obstet Gynecol 1998; 91:112–114.

10. Koenig JM, Keenan WJ. Group B streptococcus and early-onset sepsis in hte era of maternal prophylaxis. Pediatr Clin North Am 2009 June; 56 (3): 689-708.

11. Yancey MK, Schuchat A, Brown LK, Ventura VL, Markenson GR. The accuracy of late antenatal screening cultures in predicting genital group B streptococcal colonization at delivery. Obstet Gynecol 1996; 88: 811–815.

12. Hager WD. Prevention of perinatal group B streptococcal infection: Current controversies. Obstetrics and Gynaecology 2000; 96 (1): 141-145.

13. Philipson EH, Palermino DA, Robinson A. Enhanced antenatal detection of group B streptococcal colonization. Obstet Gynecol 1995; 85: 437–439.

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