TY  - JOUR
ID  - myais2257
UR  - http://ejum.fsktm.um.edu.my/ArticleInformation.aspx?ArticleID=608
IS  - 1
A1  - Gam,  Lay Harn,  
A1  - Aishah Latiff,  
Y1  - 2005///
N2  - As a consequence of the abused of human chorionic gonadotropin ?hCG) by male athletes, a reliable detection method for ?hCG is highly desired in sport testing. hCG is misused by male athletes to stimulate endogenous secretion of testosterone, which led to the ban of the hormone by the International Olympic Committee (IOC) in 1987. The present study demonstrated mass spectrometric characterization of hCG. The feasibility of tryptic peptides of hCG as marker were investigated. The fingerprints of peptides which reveal in their amino acid sequences were obtained to provide an unequivocal identification and confirmation of hCG. It is through this technique that 63% and 91% respectively of the amino acid sequence of alpha- and beta-subunit of hCG were determined.
PB  - Malaysian Society for Biochemistry and Molecular Biology
JF  - Malaysian Journal of Biochemistry and Molecular Biology
VL  - 12
KW  - Human Chorionic Gonadotropin
KW  -  Tandem mass spectrometry
SN  - ISSN 1511-2616
TI  - Identification and Confirmatory Method for Human Chorionic Gonadotropin (hCG) using HPLC/MS/MS Analysis
SP  - 25
AV  - none
EP  - 30
ER  -