%0 Journal Article
%@ ISSN 1511-2616
%A Lee, Kheng Ji,  
%A Eshaghi, Majid,  
%A Khatijah Yusof,  
%A Tan, Wen Siang,  
%D 2005
%F myais:2271
%I Malaysian Society for Biochemistry and Molecular Biology
%J Malaysian Journal of Biochemistry and Molecular Biology
%K Filamentous phage, peptide, inhibitory activities, cell culture
%N 1
%P 20-23
%T Inhibition of Newcastle Disease Virus Propagation In Vero Cells By a Recombinant Bacteriophage And A Synthetic Peptide
%U http://myais.fsktm.um.edu.my/2271/
%V 11
%X A recombinant filamentous phage bearing the peptide sequence CTLTTKLYC has been shown to interact tightly with Newcastle disease virus (NDV). The peptide, either alone or in the phage associated form, inhibited the hemolytic activity of the virus and also its propagation in embryonated chicken eggs. Here, we demonstrate that phage bearing the peptide sequence CTLTTKLYC and a synthetic peptide derived from the sequence inhibit the infection of Vero cells by NDV.
%Z This study was supported by the IRPA grant 01-02-04-003 BTK/ER/006 from the Ministry of Science, Technology and Innovation, Malaysia.